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Potential side effects also depend greatly on where the steroid injection is taken. It is common for steroids to cause serious side effects if taken from a contaminated place or injection site. This is a matter of considerable concern to practitioners, veterinarians, and patients. Because it is more difficult to get a perfect dose, it may take some time for a doctor to know when a patient is safe to use. Doctors also often have varying standards when evaluating steroid dosage. Some veterinarians may be hesitant to prescribe steroids if there isn't sufficient evidence that they have been well studied. Can I Get Steroid Sudden Death Syndrome (SDS). What Is SDS? Many young veterinarians have had contact with a patient with SDS who has died of heart failure. It is a condition that usually gets its name from a sudden death associated with an increase in heart rate (from less than 80 beats to more than 160). This increase often does not occur after a patient loses consciousness, but rather after a large dose of steroid is given. There are a number of known causes of SDS, including: Carcinogenic drugs (alcohol, opioids, or tranquilizers, among others). Alcohol and sedators such as benzodiazepines. Anticholinergics or antipsychotics. Antidepressant-related brain stimulation. Chemical irritants (particularly lithium and aspirin). Certain immunosuppressant medications (such as beta-blockers and corticosteroids). Phenosin inhibitors (for example, propionibine, neprilysin, and erythromycin). Phenylenediamine and phenylephrine are antihistamines that can cause SDS. Many of these drugs are used in combination with other drugs, especially the more sedating tranquilizers. Serendipitously, the elderly are especially prone to SDS, because the heart has more trouble pumping blood to the rest of the body. It is possible that an elderly person may develop hypercardia or increased heart rate, leading to SDS. Steroid Use and the Cardiovascular System: An Important Consideration It is well known that people with underlying heart disease have an increased risk of cardiac events from prolonged use of the same drug or from taking the drug for a longer than usual period.1,2 Also, a long-term use of steroid drugs may have a significant, but unknown, effect on other organ systems and the cardiovascular system itself. Similar articles:
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